Impact of diabetes mellitus on acute and short term left ventricular longitudinal systolic strain recovery after percutaneous coronary intervention in ischemic hypertensive patients

Alkhateeb, Areej; Abd Elrady, Nihal Salah; Ali, Ahlam Mohammed Sabrah; Hashim, Abdel Kader Ahmed

doi:10.21608/svuijm.2023.202042.1556

Impact of diabetes mellitus on acute and short term left ventricular longitudinal systolic strain recovery after percutaneous coronary intervention in ischemic hypertensive patients

Document Type : Original research articles

Authors

¹ Cardiology Unit, Internal Medicine department, Faculty of Medicine, South Valley University, Qena, Egypt

² G.I.T Unit, Internal Medicine department, Faculty of Medicine, South Valley University, Qena, Egypt

³ Nephrology Unit, Internal Medicine department, Faculty of Medicine, South Valley University, Qena, Egypt

10.21608/svuijm.2023.202042.1556

Abstract

Background: Diabetes mellitus (DM) is linked to an increased risk of cardiovascular disease and almost one-third of patients with acute myocardial infarction (AMI) may have undetected diabetes mellitus (DM) at the time of admission.
Objectives: evaluate the impact of DM on the subtle changes in left ventricular (LV) function before and post revascularization in ischemic hypertensive patients.
Patients and Methods: This was an observational prospective study performed at Qena University Hospital included 140 ischemic hypertensive patients . Patients were divided into two groups: (1) Diabetic group and (2) non diabetic group. A complete medical history, physical examination and laboratory tests were done as well as Trans thoracic Echocardiography (TTE) was done before and after PCI for each patient.
Results: In this study, there was a statistically significant (p-value < 0.05) increase in LV GLS after PCI (-14.0 ± 3.6%) when compared with GLS before PCI (-13.7 ± 1.5%) in diabetic group and highly statistically significant(p-value < 0.001) increased GLS after PCI (-15.8 ± 1.1%) when compared with GLS before PCI (-14.2 ± 0.9%) in non-diabetic group. Also we found that after PCI, diabetic patients had a significant improvement in LV EF and dimensions than the non-diabetic group that resulted in highly significant increase in GLS.
Conclusion: The presence of diabetes mellitus in ischemic hypertensive patients had an impact on subclinical LV function that has been improved after successful revascularization regardless the level of HbA1C.

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