Relation between Helicobacter pylori infection and non-alcoholic fatty liver Disease

Document Type : Original research articles

Authors

1 Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, South Valley University, Qena, Egypt.

2 Department of Diagnostic Radiology, Faculty of Medicine, South Valley University, Qena, Egypt.

Abstract

Background: Around the world, non-alcoholic fatty liver disease is the main cause of liver diseases. A substantial relationship between NAFLD and H.pylori infection has been discovered recently.
Objectives: We aimed to explore the relationship between H.pylori infection and NAFLD in Egyptians.
Patients and methods: A case-control study involved 200 patients who underwent Oesophagogastroduodenoscopy. We divided Participants into 2 groups: Group A: contained 100 patients with confirmed H Pylori infection, Group B: contained 100 patients without H.Pylori infection. We diagnosed Fatty liver by ultrasonography.
Results: Our study results showed that prevalence of non-alcoholic fatty liver disease (NAFLD) was similar in patients with H.pylori infection in comparison to control group (16% Vs 12% in GroupA and B, respectively). We found that the prevalence of dyslipidemia was higher in patients with H.pylori infection in comparison to control group.
Conclusion: There is no significant relationship between H.pylori infection and non-alcoholic fatty liver disease (NAFLD). Dyslipidemia was higher in patients with H.pylori infection than in healthy persons.

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