Placental Pathology in Pregnancy-Induced hypertension

Mohamed, Amany M.; Ali, Abd El-Naser.A.; Nasreldin, Magda H.

doi:10.21608/svuijm.2020.123731

Placental Pathology in Pregnancy-Induced hypertension

Document Type : Original research articles

Authors

¹ Pathology Department, Faculty of Medicine, South Valley University, Qena, Egypt

² Obstetrics & Gynecology Department, Faculty of Medicine, South valley University Qena, Egypt

³ Pathology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt

10.21608/svuijm.2020.123731

Abstract

Background: Hypertensive disorder in pregnancy is reflected in placenta in a significant way both
macroscopically and microscopically.
Study Design:A prospective observational study.
Study setting:Pathology department in collaboration with the Obstetrics and Gynecology department at
Qena university hospital, South Valley University, Qena, Egypt.
Duration: From May 2019 to August 2020.
Patients and method(s): This study was conducted on 50 cases of pregnant women with hypertension (mild,
severe, eclampsia) and placental changes detected microscopically by H&E stain.
Result(s): among 50 placentas studied, we found that infarction present in 16(59.3%) cases of mild
hypertension, 10(62.5%) cases of severe hypertension and 7 (100.0%) cases of eclampsia. Calcification
was found in 9(33.3%) cases of mild hypertension, 12(75.0%) cases of severe hypertension and 7(100.0%)
cases of eclampsia.
Conclusion: calcification and infarction were present in placenta of hypertensive pregnant women and
increased with increased severity of hypertension.

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