Document Type : Original research articles
Authors
1
Clinical Oncology & Nuclear Medicine Department, Faculty of Medicine, South Valley University, Qena, Egypt.
2
Public health and Community Medicine Department , Faculty of Medicine , South Valley University,Qena, Egypt.
3
Clinical Oncology & Nuclear Medicine Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Abstract
Background: Breast cancer is a significant global public health issue. In Egypt, Among female malignant tumors, it’s the most prevalent cancer.
Objectives: Determine age group of high incidences of breast cancer and assess breast cancer risks in different ages.
Patients and methods: A retrospective analysis among 510 women with proved breast cancer at our department. An interviewer-administered questionnaire and medical records from archive were used to collect data.
Results: Ages ranged from 32-79. Maximum incidence of breast cancer 28.8% is found in women aged 50-59. Majority of examined women were married 90.8%, and 32.9% were premenopausal. Mean BMI was 26.3 ± 2.9. Among women in study, 29% had personal or familial breast cancer history, 35.7% were regular users of oral contraceptives. ER: +VE, PR: +VE, HER2: -VE was the most frequent immunophenotyping. T2N1M0 was the most frequent grade. There was a strong correlation between genetic predisposition to breast cancer, overweight, menstruation at young age, and using oral contraceptives. Breast cancer rates were compared between Women of Various Ages: Obesity, single marital status, low socioeconomic status was seen for women ages 31-50 and 51-79. Oral contraceptive use, early menarche, positive family history of breast cancer, were all significant predictors of breast cancer in women aged 29–30.
Conclusion: Women between age of 50-59 have a 28.8% higher likelihood of acquiring breast cancer, then 40–49-year-old women is 28%. Our research showed that early menarche, obesity, oral contraceptive use, and family history of the disease were important predictors of breast cancer.
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