Effects of Bariatric Surgery on Hormonal and Joint Co-morbidities in Obese Patients in Al-Madinah Region (Western Saudi Arabia): A tertiary Hospital Experience

Almughamsi, Asim Mukhideer; Aly, Mohamed Abdelnaem; Alfarsi, Muayad Ahmed; Alahmari, Ahmed Modawi; Alhazmi, Rema Mohammed; Alhazmi, Shaden Mohammed; Makhdom, Raghad Abdulrazaq; Alfadhli, Reema Ahmed; Aljohani, Lujain Abdulaziz; Elmehallawy, Ghaidaa Salem; El Sayed, Salah Mohamed; Saad, Alfarazdeg Ageed; Abdallah, Mohamed Ramadan; El-Shazley, Momen; Mohamed, Magdy A.; Elhassan, Yasir; Afifi, Tarik Mohamed; Donkol, Abdel-Raheem

doi:10.21608/svuijm.2024.325163.1989

Effects of Bariatric Surgery on Hormonal and Joint Co-morbidities in Obese Patients in Al-Madinah Region (Western Saudi Arabia): A tertiary Hospital Experience

Document Type : Original research articles

Authors

¹ Department of General surgery, Taibah college of Medicine, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia.

² Department of General surgery, Taibah college of Medicine, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia.& Department of General surgery, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt.

³ Department of General surgery, King Salman bin Abdulaziz Medical City hospital, Al-Madinah Al-Munawwarah, Saudi Arabia.

⁴ MBBS, Taibah college of Medicine, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia.

⁵ Department of Clinical Biochemistry, Taibah college of Medicine, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia . & Department of Clinical Biochemistry, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt.

⁶ Department of Clinical Biochemistry, Taibah college of Medicine, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia

⁷ Division of Pediatric Surgery, Department of General Surgery, Al-Rayyan College of Medicine, Al-Rayyan Medical Colleges, Al-Madinah Al-Munawwarah, Saudi Arabia.& Department of Pediatric Surgery, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt.

⁸ Pulmonology Unit, Department of Internal Medicine, King Salman Specialities Hospital, Hail Health Cluster, KSA.

⁹ OB/GYN Consultant, Maternity and Children Hospital, Hail Health Cluster, Hail, Saudi Arabia. & Department of Obstetrics and Gynecology, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt

¹⁰ Associate Professor, Medical Education Director & Clinical neuroanatomist, Department of Anatomy, Taibah college of Medicine, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia

¹¹ Thoracic Surgery Consultant, Department of Cardiothoracic Surgery, Najran Health Cluster, Ministry of Health, Najran, Saudi Arabia. & Department of Cardiothoracic Surgery, Faculty of Medicine, Sohag University, Sohag, Egypt.

¹² Department of General Surgery, King Fahd Hospital, Al-Madinah Health Cluster, Al-Madinah Al-Munawwarah, Saudi Arabia. & Department of General Surgery, Aswan Faculty of Medicine, Aswan University, Aswan, Egypt.

10.21608/svuijm.2024.325163.1989

Abstract

Background: As a major global public health concern, obesity is related to a number of hormonal comorbidities as well as a lower quality of life in older children and adults. Weight loss with bariatric surgery has proven to be a successful intervention. Few reports exist on hormonal and osteoarthritis comorbidities in Al-Madinah Region (western Saudi Arabia) before and after bariatric surgery.
Objectives: This study aimed at determining the prevalence of hormonal and joint co-morbidities in obese patients before and after bariatric surgery in Al-Madinah region.
Patients and methods: In older children (14-16 year) and adults, a retrospective analysis was carried out using data on hormonal co-morbidities prevalence as hypothyroidism, polycystic ovary syndrome and hyperprolactinemia in addition to joint osteoarthritis and quality of life post-bariatric surgery compared to the original conditions.
Results: A total of 170 patients were included in this study. Statistically significant differences were observed in the prevalence of hypothyroidism using chi square test (p<0.05) (35 patients, 20.5% of the studied sample significantly decreased after bariatric surgery to 17 patients only, 10.0% of the studied sample) and polycystic ovary (23 individuals 13.5% of the sample under study dramatically dropped to 6 patients only, 3.5%) chi square test (p<0.01). Prevalence of hyperprolactinemia and joint osteoarthritis decreased strongly but not significantly after bariatric surgery. Quality of life improved after bariatric surgery.
Conclusion: The prevalence of hormonal and joint co-morbidities declined after bariatric surgery while quality of life improved. This supports the advantages of bariatric surgery and obesity management while considering these comorbidities.

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