Relationship between Helicobacter pylori infection and iron deficiency anemia in children: A review article

Document Type : Reviews Articles.

Authors

1 Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt

2 Department of Clinical Pathology, Faculty of Medicine, South Valley University, Qena, Egypt.

Abstract

Background: One of the greatest prevalent chronic illnesses, Helicobacter pylori (H. pylori), affects around 50% of people globally. Early infancy is when this virus is most often contracted, particularly in developing nations. The frequency of H. pylori varies greatly across nations; in underdeveloped nations, 50% of children are infected by the time they become 10 years old. The beginning of several Gastro intestinal tract pathologies, including active persistent gastritis, peptic ulcers, gastric carcinoma, extra-gastric symptoms, thrombocytopenic purpura, and anemia owing to inadequate iron reserves iron deficiency anemia (IDA), is discovered to be related with H. Pylori infections. A link between anemia and H. pylori infections is supported by a variety of data from epidemiological and clinical research.
Objectives: To highlight connection between Helicobacter pylori infections and IDA in children, and to explore the mechanism of this association.
Conclusion: Infection with Helicobacter pylori is substantially linked with iron deficiency anemia in children.

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