Severity of Coronary Artery Disease associated with Non-Alcoholic Fatty Liver

Document Type : Original research articles

Authors

Internal Medicine Department, Qena Faculty of Medicine,South Valley University

Abstract

Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is closely related to several metabolic disorders and is also associated with increased risk of cardiovascular disease (CVD), including coronary artery disease (CAD). Patients and methods: This was a prospective study involving patients who underwent coronary catheterization and had proven coronary artery diseases.All patients were subjected to abdominal ultrasonography and transient elastography to detect NAFLD and grading of steatosis . Results: A total of 100 patient, with mean ageof 47.9 ± 8.4 years, 70% were males , 70% were diabetics. According to ultrasonographic findings, there were 58 patients (58%) normal and 42 patients (42%) with fatty liver. As regard degree of steatosis, there were 12 patients (12%) of S0, 38 patients (38%) of S1, 22 patients (22%) of S2 and 28 patients (28%) of S3.The mean of Genseni score was 50.9.There was highly statistical significant correlation (p-value < 0.001) between degree of steatosis and Genseni score in studied patients,the mean of Gensini score was 10.5, 21.7, 57.6 and 102.6 in Grade S0, S1, S2 and S3 respectively. Conclusion: The present study indicated a Statistically significant correlation between CAD and NAFLD.

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